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Senior Scientist, In Vitro Biology

The Biology group at Pipeline Therapeutics is currently seeking a Senior Scientist to join our research team in San Diego. The successful candidate will play a key role in our small molecule drug discovery effort focusing on neuro-regenerative therapies. This is a lab-based position and responsibilities will include designing, managing, and executing in vitro assays to drive our drug discovery programs. The successful candidate will be able to investigate literature and propose new directions for the team to pursue.

Key Responsibilities
Conduct in vitro assays within the Biology team from primary in vitro screens through mechanistic query of disease relevant biology. This will include working with the research team to identify and implement new assays systems, as well as providing scientific input into cross-functional areas. Provide timely presentations of research rationale, key data, issues, and accomplishments to members of the discovery team and to the broader organization. Maintain a research environment that is safe and conducive to the open sharing of ideas and responsibilities. The candidate will also manage and analyze experimental data, write and submit papers to scientific journals, write reports for regulatory submission, and present experimental results at scientific conferences.


PhD or equivalent in Neuroscience, Molecular or Cellular Biology, or related disciplines with 2+ years of experience in the biotech or pharmaceutical industry or equivalent postdoctoral work.

4-10 years’ experience in industry is preferred. 2+ years in drug discovery and neurodegenerative disease areas is highly desired. Demonstrated success in identifying and establishing screening assays (HTS not required). Experience with primary neurons or tissue models. Proficiency in laboratory bench skills such as RNA analysis, enzyme assays, kinetic analyses, microscopy, and/or quantitative histology is desired. Experience with ex vivo or in vivo brain or spinal cord systems, or human IPSCs is a bonus. Familiarity with quantitative small molecule drug discovery, statistical analysis, and biomarker discovery. Strong communication skills including generating slide decks and presentation.

Strong experimental background and experience in hypothesis-driven biological/translational research with a demonstrated ability to execute well-designed, creative experiments. Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast-paced and dynamic, team-oriented environment. Collaborative and have excellent communication and interpersonal skills. Can prioritize multiple high priority tasks effectively. Ability to integrate complex scientific ideas, generate testable hypotheses, and execute broad understanding of drug discovery and development in pre-clinical development. Strong problem-solving skills with a high level of creativity and productivity.

The expected salary range for this role for employees located in the San Diego area is $110,000 – $120,000.  Additionally, this position is eligible for an annual performance bonus.  Determination of the starting salary will depend upon a variety of job-related factors, which may include professional experience, skills and job location.  The expected salary range for this role may be modified in the future.

Pipeline Therapeutics offers an excellent compensation and benefits package. Please submit your resume or CV and supporting documents to info@pipeline-tx.com.