Continuem Therapeutics
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Lysophosphatidic Acid Receptor Subtype-1 Antagonist PIPE-791 Reduces Neuropathic Pain in Macaques

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Discovery of a brain penetrant small molecule antagonist targeting LPA1 receptors to reduce neuroinflammation and promote remyelination in multiple sclerosis

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PIPE-791 inhibits LPA1 to promote myelination and limit neuroinflammation

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PIPE-791, a potent brain-penetrant selective LPA1 antagonist, reduces neuroinflammation in vivo 

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Lysolecithin (LPC) induced demyelination of the optic chiasm as a model to evaluate remyelinating agents

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Contineum Therapeutics
©2025 Contineum Therapeutics     linkedin    Terms of Use    Privacy Policy
logo
  • About
    • About Us
    • Leadership
    • Board of Directors
    • Scientists and Staff
  • Approach
  • Programs
    • Overview
    • PIPE-791
    • CTX-343
    • PIPE-307
    • Publications
  • Patients
  • Investors
  • News & Events
  • Careers
  • Contact